Programming T cells in situ – Nature.com
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Programming T cells in situ
Nature.com Smith et al. describe a method of programming T cells in situ using DNA-carrying nanoparticles. Nanoparticles were targeted to T cells and loaded with DNA encoding the leukaemia-specific CD19−4-1BB−CD3ζ (194-1BBz) CAR; this DNA sequence was … |
