New study reveals key steps in CRISPR-Cas3 function at near-atomic resolution – Phys.Org
Phys.Org |
New study reveals key steps in CRISPR-Cas3 function at near-atomic resolution
Phys.Org Cryo-electron microscope image of CRISPR in a full 'R-loop' conformation. DNA (orange and red) is unwound and compared to CRISPR RNA (blue), to determine if the target DNA should be cut by the Cas3 enzyme. Credit: Liao lab/Harvard Medical School. New gene-editing tool could cure disease. Or customize kids. Or aid bioterrorism. |
