Tuning ITAM multiplicity on T cell receptors can control potency and selectivity to ligand density – Science
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Tuning ITAM multiplicity on T cell receptors can control potency and selectivity to ligand density
Science … T cell signaling at the single-cell level. The experimental data fit computational models predicting that increasing ITAM number influenced the efficiency of signal transduction, but not the signal amplitude. Application of these results to human … |
