Stem cells SIRT7, the UPR and HSC ageing – Nature.com
Nature.com |
Stem cells SIRT7, the UPR and HSC ageing
Nature.com A study in Science now shows that the histone deacetylase sirtuin 7 (SIRT7) promotes the regenerative capacity of aged haematopoietic stem cells (HSCs) by driving a regulatory branch of the mitochondrial unfolded protein response (UPRmt). Mohrin et al. |
