All posts by: Michael Zand

About Michael Zand

T cells — burn fat, get fit – Nature.com

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2017-10-06 NEWS

T cells — burn fat, get fit
Nature.com
… partially preserve effector functions in a hypoglycaemic and hypoxic TME, and that metabolic reprogramming of these cells using a PPARα agonist improves their antitumour functionality and increases efficacy of PD1-targeted immunotherapy in melanoma.

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2017-10-06 NEWS

Technology Networks

Dentists Get Cracking on the Stem Cell Front
Technology Networks
Stem cells. Few research discoveries hold as much promise of single-handedly expanding medical treatment options as they do. Miraculously able to act as transformers—either re-creating or morphing into a variety of cell types found within the

Continue reading

2017-10-06 NEWS

Technology Networks

Dentists Get Cracking on the Stem Cell Front
Technology Networks
Stem cells. Few research discoveries hold as much promise of single-handedly expanding medical treatment options as they do. Miraculously able to act as transformers—either re-creating or morphing into a variety of cell types found within the

Continue reading

2017-10-06 NEWS

Broad Researchers Developing Pooled Genomic Perturbation Screening Method Using CRISPR
GenomeWeb
“Specifically, we will screen pooled genomic perturbations (with barcoded CRISPR-Cas9 single guide RNAs) using microscopy to read out phenotypes and to identify perturbed genes at the single-cell level,” they wrote in the abstract. “Perturbed genes

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