Blunting CRISPR’s ‘scissors’ gives new insight into autoimmune … – Science Daily
Medical Xpress |
Blunting CRISPR’s ‘scissors’ gives new insight into autoimmune …
Science Daily A research team has used a modified version of the gene-editing technique CRISPR to find enhancers — not by editing them but by prompting them into action. CRISPRa Method Identifies Gene Enhancers Affecting T Cell …GenomeWeb |
|
US clears first ‘living drug’ for tough childhood leukemia
Orlando Sentinel The CAR–T cell treatment developed by Novartis Pharmaceuticals and the University of Pennsylvania is the first type of gene therapy to hit the U.S. market — and one in a powerful but expensive wave of custom-made “living drugs” being tested against … |
FierceBiotech |
‘Hit-and-run’ gene therapy nanoparticles could enhance CAR–T treatments
FierceBiotech Personalized cancer treatments known as CAR–T cells (chimeric antigen receptor T cells) have dominated the headlines lately, thanks to Novartis’ tisagenlecleucel, which won an early approval from the FDA for the treatment of leukemia on Aug. 30. ‘It’s a new era for cancer care’: US clears first gene therapy for aggressive childhood leukemiaDaily Mail |
|
‘Historic Action’: FDA Approves First CAR–T Therapy
Regulatory Focus In addition to Kymriah’s approval, FDA also announced the expanded approval of Roche’s Actemra (tocilizumab) to treat CAR T-cell-induced severe or life-threatening cytokine release syndrome in patients 2 years of age or older. “In clinical trials in … |
Olean Times Herald |
A Look at How CAR-T Cell Therapy Works | | oleantimesherald.com
Olean Times Herald The Food and Drug Administration has approved the first treatment that genetically engineers patients’ own blood cells into an army of assassins to seek and … |
Quartz |
Scientists are ready to treat Parkinson’s with stem cells
Quartz Researchers think they’ve found a way to more permanently treat an incurable movement disorder, by transplanting reprogrammed neurons made from stem cells into patients’ brains. Parkinson’s is a neurological disorder that affects roughly 10 million … Trials to inject stem cells into brains of Parkinson’s patients could begin next yearTelegraph.co.uk Parkinson’s symptoms reversed in monkeys by groundbreaking new treatmentThe Independent ‘Reprogrammed’ stem cells fight Parkinson’s disease in monkeysWHTC The San Diego Union-Tribune –Medical Xpress –BBC News all 13 news articles » |
Genetic Engineering & Biotechnology News (blog) |
CRISPR Genome Scan Reveals Key Immune System Regulators
Genetic Engineering & Biotechnology News (blog) While much of the excitement around CRISPR gene editing focuses on its medical and public health applications, the ability to precisely edit virtually any DNA sequence is a revelation for basic research. In the latest demonstration, researchers at the … |
U.S. News & World Report |
FDA Approves Gene-Altering Leukemia Drug
U.S. News & World Report The Food and Drug Administration on Wednesday approved its first gene therapy drug in the United States that will treat childhood leukemia. Novartis drug Kymriah works by genetically modifying pediatric and young adult patients’ blood cells to attack … |