All posts by: Michael Zand

Gene therapy skin grafts for obesity and diabetes
BioNews
A proof-of-concept study in mice has demonstrated how skin grafts could deliver gene therapy for obesity and diabetes. ‘We think this platform has the potential to lead to safe and durable gene therapy, in mice and we hope, someday, in humans, using …
New gene therapy through skin transplants can help improve …TheHealthSite
Gene therapy via skin may treat diabetes, obesityThe Statesman
Gene therapy via skin may treat diabetes, obesity – appsforpcdaily.comAppsforPCdaily
domain-B –Tech Times
all 9 news articles »

Scientists Discover Dozens of New Genes that Create T-Cell Resistant Cancer
NYU News (press release)
“We cast a wide, deep net and conducted an unbiased survey of all of the 19,000 genes in the cancer’s genome – not just the genes that are known to be involved in creating immunotherapy-resistant tumors,” explains the study’s senior author, Nicholas P.

Durable Immunotherapy Benefits Foster Excitement in Bladder Cancer, Despite Low Response Rates
Targeted Oncology
While immunotherapy agents have only demonstrated a clinical benefit for approximately 15% to 20% of patients with urothelial carcinoma, it’s the durable responses observed in these patients that have doctors excited, says Arlene Siefker-Radtke, MD.

NCI study identifies essential genes for cancer immunotherapy
National Institutes of Health (press release)
A new study identifies genes that are necessary in cancer cells for immunotherapy to work, addressing the problem of why some tumors don’t respond to immunotherapy or respond initially but then stop as tumor cells develop resistance to immunotherapy.

NCI study identifies essential genes for cancer immunotherapy
EurekAlert (press release)
A new study identifies genes that are necessary in cancer cells for immunotherapy to work, addressing the problem of why some tumors don’t respond to immunotherapy or respond initially but then stop as tumor cells develop resistance to immunotherapy.

CRISPR Screen Identifies Top 100 Essential Genes for Cancer Immunotherapy
Genetic Engineering & Biotechnology News
To try to understand the genetic basis of these differing responses, scientists at the U.S. National Institutes of Health developed a genome-scale CRISPR/Cas9 screen that allowed them to knock out every single gene in a melanoma cell line and then …

and more »

MilliporeSigma to Be Granted European Patent for CRISPR Technology
Genetic Engineering & Biotechnology News
The European Patent Office has told MIlliporeSigma it intends to grant approval of its patent application covering the company’s CRISPR technology used in a genomic integration method for eukaryotic cells—the second key patent awarded in Europe …