QuartzScientists are genetically engineering immune systems to attack and destroy HIVQuartzThe experiment involved genetically modifying stem cells to produce immune-system T cells and other blood cells with a specific chimeric antigen receptor (CAR) t… Continue reading
Quartz |
Engineered Stem Cells Show Promise vs HIV (STAT
MedPage Today Genetically engineered stem cells that can target HIV and interferes with the virus’ ability to enter the cell may represent a novel treatment for HIV/AIDS, according to a report in STAT. Lab studies and administration of the chimeric antigen receptors … Scientists are genetically engineering immune systems to attack and destroy HIVQuartz |
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Why 2017 Was a Year to Remember for Juno Therapeutics
Motley Fool JCAR017, the new star of Juno’s pipeline, uses the same basic principle as JCAR015; both are chimeric antigen receptor T–cell (CAR-T) therapies that train T–cells to target cancerous cells expressing a protein called CD19, but JCAR017 uses a fixed … |
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Blockade of TNFR2 signaling enhances the immunotherapeutic effect of CpG ODN in a mouse model of colon cancer
Science Cancer immunotherapy attempts to stimulate the patient’s own immune system against a tumor, but despite its potential, the clinical efficacy of immunotherapy has been extremely limited. In some cases, the patient’s own immune system can counteract … |
EurekAlert (press release) |
NIH discovery brings stem cell therapy for eye disease closer to the clinic
EurekAlert (press release) “We now have a better idea about how to generate and replace RPE cells, which appear to be among the first type of cells to stop working properly in AMD,” said the study’s lead investigator, Kapil Bharti, Ph.D., Stadtman investigator at the NEI. Bharti … |