Lunatic fringe gene plays role in regulating fate of neural stem cells – News-Medical.net
|
Lunatic fringe gene plays role in regulating fate of neural stem cells
News-Medical.net Researchers at Baylor College of Medicine and Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital have developed a novel mouse model that for the first time selectively identifies neural stem cells, the progenitors of new … |
Medical Xpress |
Human CAR–T Cell Glioblastoma Trial Generates Clues for Improving Treatment
Genetic Engineering & Biotechnology News A chimeric antigen receptor T–cell (CAR-T) therapy for glioblastoma (GBM) successfully crossed the blood–brain barrier to reach tumors in the brain, appeared safe, and reduced levels of its epidermal growth factor variant III (EGFRvIII) tumor target in … Combining CAR T cells with existing immunotherapies may overcome resistance in glioblastomasMedical Xpress |
Medical Xpress |
Combining CAR T cells with existing immunotherapies may overcome resistance in glioblastomas
Medical Xpress Over the past two years, investigators from the Perelman School of Medicine at the University of Pennsylvania have reported results from a human trial in GBM using chimeric antigen receptor (CAR) T cell therapy, through which patients’ own T cells were … Human CAR–T Cell Glioblastoma Trial Generates Clues for Improving TreatmentGenetic Engineering & Biotechnology News |
Harvard Gazette |
Discovery of new drug may release immune cells destroy cancer cells
Harvard Gazette “PD-1 checkpoint inhibitors have transformed the treatment of many cancers, and opened the door to the possibility that immunotherapy will form part of the cure for cancer,” says Haining, senior author on the new paper, who is also associate professor … |
Medical Xpress |
Novel CRISPR-Cas9 screening enables discovery of new targets to …
Medical Xpress A novel screening method developed by a team at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center—using CRISPR-Cas9 genome editing … |
|
FDA Advisory Committee Recommends Approval of CAR–T Cell Therapy and Two New Biosimilars
Lexology (registration) The FDA’s Oncologic Drug Advisory Committee (“ODAC”) held a public meeting on Wednesday, July 12, 2017, to consider Novartis’ biologic license application (BLA 125646) for tisagenlecleucel (CTL019), an investigational chimeric antigen receptor T cell … |
IFLScience |
Promising Treatment For Leukemia Leads To Remission In Clinical …
IFLScience An exciting therapy for leukemia once again shines a light on its efficacy – this time, nearly 71 percent of terminal leukemia patients saw their tumors sh. |
LancasterOnline |
McCaskey grad writes new book on CRISPR and genome engineering
LancasterOnline Now, the McCaskey High graduate has co-written a new book about gene editing and CRISPR. “A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution” was written by microbiologist Jennifer Doudna and Sternberg. The book … |