CRISPR hack unearths gems buried in ‘dark genome’ – Spectrum
Spectrum |
CRISPR hack unearths gems buried in ‘dark genome’
Spectrum Tweaks to the CRISPR gene-editing system allow researchers to identify stretches of DNA that regulate gene expression. Researchers could use the method to find sequences that control genes tied to autism. The CRISPR system uses RNA guides to direct … |
pharmaphorum |
Novartis considers “pay-for-performance” for CAR–T
pharmaphorum Novartis is considering a “pay-for-performance” pricing scheme if its CAR–T therapy gets approved, following trial results published earlier this week. Results of the phase 2 JULIET study of 51 patients in relapsed or refractory diffuse large B-cell … CAR–T pricing decision looms large for NovartisThe Pharma Letter (registration) |
BioPharma-Reporter.com |
Lonza plugs EU cell and gene therapy manufacturing gap through PharmaCell buy
BioPharma-Reporter.com The deal sees Switzerland-headquartered contract development and manufacturing organisation (CDMO) add the assets and staff of PharmaCell to strengthen its cell and gene therapy offerings. “We had a manufacturing gap in the European market, … |
Science Daily |
World first: Stem cell treatment for lethal STAT1 gene mutation shows ‘disappointing,’ but promising results
Science Daily Dr. Okada, who first discovered the STAT1 gain of function mutation in 2011, says that “Overall, this result is disappointing — but the fact five patients were cured proves that treatment with stem cells can work, and we now need to learn from these … |
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CRISPR pioneer Feng Zhang’s lab spawns a new Cambridge biotech
Boston Business Journal They include Zhang, a co-inventor of CRISPR/Cas9, the experimental and potentially revolutionary technology for cutting out and replacing parts of genes. Two graduate students who work in Zhang’s lab and have conducted research related to CRISPR, … |