Science MagazineRefining cell therapyScience MagazineT cells engineered to express chimeric antigen receptors (CARs)—synthetic receptors consisting of a tumor-specific extracellular antibody fragment fused to the signaling chain from the native T cell … Continue reading
Science MagazineChemically induced proximity in biology and medicineScience MagazineThe physical distance, or proximity, between molecules often directs biological events. The development of membrane-permeable small molecules that reversibly regulate p… Continue reading
Investor’s Business Daily |
Could Tiny Rivals Make Gilead, Novartis Obsolete In Oncology?
Investor’s Business Daily Novartis and Gilead are still in the early stages of launching their respective drugs called Kymriah and Yescarta, which are known as CAR–T drugs. But Cellectis (CLLS) and Crispr Therapeutics (CRSP) — each with a tiny fraction of their rivals’ market … |
MD Magazine |
The Gene Therapy Dam is Finally Breaking
MD Magazine When Stephan Grupp, MD, PhD, began enrolling patients in the clinical trials for what would become the first-ever gene therapy approved by the US Food and Drug Administration (FDA), his problem wasn’t finding volunteers — it was reigning in … |