Translational genetics: CRISPR therapies — making the grade not the cut – Nature.com
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Translational genetics: CRISPR therapies — making the grade not the cut
Nature.com Modulation of transcription by CRISPR systems typically involves a nuclease-dead Cas9 (dCas9) fused to a protein domain that alters transcription, such as a transcriptional activator, repressor or histone modifier. This fusion protein is then guided to … |
